Amazon River Cruise with Machu Picchu

  • $3499
  • 11


On this adventure cruise through the Amazon, you’ll get to see this vast tropical rainforest like never before. Starting your journey in Cusco, discover the Sacred Valley, fascinating historic city sights, and Machu Picchu—the ancient Inca civilization surrounded by spectacular mountains. After a stay in Iquitos, embark on your exciting Amazonian cruise by sailing on the Marañon River through Pacaya-Samiria National Reserve. During this 3-night journey, you’ll head out on thrilling day expeditions via skift, boat, and hiking to find a multitude of exotic plants, unique indigenous animals, and various jungle landscapes. Your expert guides will offer their knowledge of the Amazon, making this journey insightful and unforgettable. While aboard ship, savor authentic Peruvian cuisine, unwind with the calming sounds of nature, and admire a star-filled sky each night. Click here to get an in-depth look at exactly what to expect on this tour.

Itinerary at
a Glance

  • 2 nights in the Sacred Valley
  • 1 night in Cusco
  • 1 night in Iquitos
  • 3-night Amazon Cruise
  • 1 night in Lima


  • Machu Picchu
  • 3-night Amazon River Cruise including exciting excursions
  • Amazonian Jungle Walk
  • Pisac Market & Ruins of Sacsayhuaman
  • Larco Herrera Museum

Activity Level: Explorer 

Your Tour

  • Round-trip airfare from Miami
  • Airfare taxes, fees & fuel surcharges
  • Intra-Peru flights, ground transportation, and transfers
  • 3-night Amazon Cruise
  • Accommodations at first-class hotels
  • 17 Meals: 8 breakfasts, 4 lunches, 5 dinners
  • Comprehensive sightseeing tours including admission fees
  • Expert naturalist guides on your Amazon Cruise
  • Experienced, English-speaking guides

Tour Itinerary

Depart USA

Your exciting expedition to Peru begins late this evening with an overnight flight to Lima. Your tour includes round-trip airfare from the U.S.

Arrive Peru

Welcome to Peru! Upon arrival in Lima, you’ll have a flight connection to Cuzco where you’ll be greeted at the airport and taken to your hotel in the Urubamba Valley (Sacred Valley). On the way, we’ll stop at the archaeological park of the fortress-temple Sacsayhaman which features massive stone structures arranged in a unique zig zag formation. Next, you’ll visit famous mirador (lookout) in the Sacred Valley where there is an opportunity for a great picture! Then, we’ll have an authentic welcome lunch at Hacienda Sarapampa, a private plantation dedicated to the production of…

Machu Picchu Rail Excursion

Machu Picchu

After being picked up from your hotel in the morning, you’ll board a train to Aguas Calientes, a village nestled at the foot of Machu Picchu. Admire gorgeous landscapes and snow-capped mountains during this 1.5-hour ride, which passes through the Sacred Valley. Upon arrival, a shuttle bus takes you up to see the incredible Machu Picchu ruins. Spend 3 to 4 hours exploring great viewpoints and taking in this renowned world wonder. The famous green mountains and impressive ancient structures built during the Inca civilization will simply captivate you. You’ll then head back down by bus and…

Sacred Valley/Cuzco

Today we’ll travel back to Cusco and on the way, stop at the famous Pisac Market to browse and bargain for Peruvian handicrafts such as ceramics, paintings, antiques, jewelry, and much more. We’ll also visit the Cochahuasi Animal Sanctuary to see indigenous wildlife such as Alpacas, Llamas, Condors, Andean Bears, Pumas, etc. When we arrive, you’ll check into your hotel and then venture out on a walking tour to see notable sights like the Plaza de Armas, Qorikancha temple, and more. Following this, the rest of the day is at your leisure.
Hotel Sonesta Hotel Cusco |…


This morning you’ll transfer from the hotel to the airport for your flight to Iquitos, where you’ll be welcomed at the airport and taken to your hotel. In the afternoon, set out on a city tour beginning with a stroll along the Malecón Grau promenade where you can admire fantastic views Itaya River, the old canal of the Amazon. Then, explore the city’s historic buildings and end with a stop at the Plaza de Armas where you’ll find the Iron House of Iquitos, designed by civil engineer Gustave Eiffel. Plus, you’ll take a trip to the Quistococha Zoo & Lagoon for a relaxing…

Embark on Your Amazon Cruise

Nauta – Pacaya-Samiria Reserve – Yanayacu de Yacapana

In the morning, you’ll be escorted to the airport to meet your guides and take a short flight to Nauta where you will board the La Perla cruise ship and begin your riveting adventure down the Amazon. Settle in your comfortable cabin and then head to the observation deck to start taking in the natural beauty as we sail along the Marañon River where the majestic Amazon begins. For lunch, you will have a delicious three-course meal featuring some of Peru’s best dishes while getting briefed on the itinerary and activities of the days ahead. Following lunch, you’ll set out on your first…

Amazon Cruise

Pacaya-Samiria Reserve – Yanayacu de Yacapana

Rise early this morning to begin your day with a stunning Amazonian sunrise. Head out into the Yanayacu de Yacapana once again for another exciting trek that includes extraordinary birdwatching of macaws, toucans, parrots, and more, along with sloth and monkey encounters. Then, return to the ship for a hearty breakfast as the we sail to the Ucayali River. Later, there will be another morning excursion to explore the tributaries rivers, like the Yarapa where you can observe iguanas, sloths, and other exotic creatures. You’ll return to the ship to refuel with an energizing lunch as we sail…

Amazon Cruise

Pacaya-Samiria Reserve – Yarapa River – Piranha Creek

To start the day, we’ll have an excursion through the black waters of the Yarapa river, where we will have an unforgettable experience admiring wildlife and the captivating jungle landscape. Return to the ship for breakfast, followed by a boat excursion to explore Piranha creek. After lunch aboard the boat, we’ll take a trekking tour in the jungle, where you’ll learn about medicinal plants and look for tarantulas, frogs, spiders, and many other unique creatures of the Amazon. Our naturalists will also teach you about basic survival in the jungle. Back at the ship we’ll provide live…

Disembark Cruise/Lima

After enjoying your last breakfast on board, you’ll proceed by bus from the city of Nauta to Iquitos. There we’ll stop in the Amazonian Manatee Rescue Center, where you will be able to admire this beautiful animal and learn about conservation efforts. Then, you will have a brief visit to the city of Iquitos to observe the famous houses of the rubber boom and Belen Market. Finally, arrive at the airport to board your flight to Lima where you’ll be welcomed at the airport and taken to your hotel.
Casa Andina Select Miraflores | Breakfast

Lima/Arrive in USA

On our last day in Peru, you’ll check out of hotel at noon and shortly after be picked up for a city tour through the colonial part of Lima. First, you start at the Plaza de Armas with its colonial buildings such as the Government Palace, Municipality, Palace of the Archbishop, Cathedral, and more. You’ll also visit the San Francisco Monastery with its maze of tunnels and catacombs. Finish your tour with a visit to the fascinating Larco Herrera museum, featuring more than 45,000 objects of pre-Columbian ceramics, textiles, and gold and silver pieces. In the restaurant of the museum…

Arrive USA

Arrive back in U.S. after your exciting Amazon adventure.

Guided Tour Pricing

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2021 2021 w/ eCheck Discount Sale After Sale
October 5 October 15 Oct 5 -
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$3,499 $3,599 $3,999

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November 2 November 12 Nov 2 -
Nov 12
$3,599 $3,699 $4,099

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Rates are per person based on double occupancy.
Single room supplement is $799.

The high altitudes reached on this trip (up to 11,000 feet above sea level) requires that you be in good physical condition to fully enjoy the trip. We strongly suggest that you consult a physician regarding any concerns prior to making a reservation.

For more information on this tour, please contact us here or call us during business hours (Mon-Fri, 9:00am – 5:30pm EST) at 800-337-7773.

Reservations and Payments 
Reservations can be made by phone (1-800-337-7773) and will be confirmed upon receipt of your non-refundable, non-transferable deposit, which must be received at the time of reservation. Deposits are $99 per person for all 2021 departures, and $300 per person for all 2022 departures. Full payment is due 90 days prior to departure. Baggage fees may apply. Space and prices subject to availability. Please see the smarTours Terms and Conditions for complete booking information.

Optional Tours Customize your trip with these optional tours.

Hike Andenas de Yucay

  • From approx. Free 3

Stretch your legs during a short stroll (about an hour) and enjoy nature and the beautiful landscapes near your hotel. Behind the Plaza of Yucay is an impressive group of terraces that follow the outline of the mountain and are still in use by the locals. Part of the walk is also along a water channel.

Quistacocha Lagoon & Zoo

  • Iquitos
  • From approx. 15 sols (approx. $5 USD) Per Person

Located around the lake of Quistococha, you can enjoy the artificial beach of Tunchi Playa and swim in the warm waters of the lagoon at the center of the complex. You’ll also take a guided tour of the museum, aquarium, and zoo. See many indigenous animals including snakes, monkeys, lizards, iguanas, various species of birds, manatees, pink dolphins, and more! A boxed lunch will be provided.